They include systemic sclerosis, sjogrens syndrome, inflammatory myositis, primary vasculitis. These disesases can also effected to multiple organs of the body similar to other rheumatic diseases. Early diagnosis and treatment prevents suffering and improving survival.
Systemic sclerosis: These patients presents commonly with raynauds, gastric upset, skin tightness, arthritis.
Sjogrens syndrome: It affects females most commonly. They have profound fatigue overtiredness, dryness of mouth and eyes, low potassium levels which can manifest as paralysis.
Inflammatory Myositis: These diseases effect females predominantly. It mainly targets muscles of body manifesting as extreme muscle weakness. It is also characterised by various types of skin rash similar to lupus.
Vasculitis: These are multisystem life threatening diseases predominantly targeting blood vessels. They can have varied presentations and are associated with high mortality.